Mouse Anti-Human CFHR1 Monoclonal Antibody (TJL-87)(Cat#: CTMM-0322-JL494)

Name: Mouse Anti-Human CFHR1 Monoclonal Antibody (TJL-87)
SKU: CTMM-0322-JL494
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Complement CFHR1 Monoclonal antibody (TJL-87) generated from the Mouse. The antibody can be used for ELISA.

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Specifications

Clonality	Monoclonal
Clone	TJL-87
Host Animal	Mouse
Isotype	IgG1
Immunogen	Human Complement Factor H
Species Reactivity	Human
Applications	ELISA
Application Notes	The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Complement CFHR1.
Purity	≥95% as determined by SDS-PAGE
Conjugation	Unconjugated
Format	Liquid
Size	100 µg
Storage	Store at 4°C.
Type	Primary Antibody

Target

Target Name	CFHR1
Alternative Names	Complement Factor H-Related 1 Pseudogene; H Factor (Complement)-Like 1; H Factor (Complement)-Like 2; H Factor-Like Protein 1; H-Factor-Like 1; Complement Factor H-Related Protein 1; FHR-1; H36; CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P
Gene ID	3078
UniProt ID	Q03591

Information

Introduction

Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene. This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.