Mouse Anti-Human Clusterin Monoclonal Antibody (CTJS-270)(Cat#: CTA-193)
This product is an unconjugated anti-Human Clusterin Monoclonal antibody (CTJS-270) generated from the Mouse. The antibody can be used for WB; ELISA; FC; IF; IHC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-270 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization. |
| Species Reactivity |
Human |
| Applications |
WB; ELISA; FC; IF; IHC |
| Application Notes |
WB: 1 µg/mL
ELISA: 1:2000
IF: 1:10-1:500
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Clusterin. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store at 4°C. Do not freeze. |
| Type |
Primary Antibody |
Target
| Target Name |
Clusterin |
| Alternative Names |
Testosterone-Repressed Prostate Message;Clusterin (Complement Lysis Inhibitor, SP-40, 40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J); Apolipoprotein J; Complement-Associated Protein SP-40, 40; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Sulfated Glycoprotein 2; Ku70-Binding Protein 1; NA1/NA2; TRPM-2; APOJ; KUB1; CLI; Aging-Associated Gene 4 Protein; Aging-Associated Protein 4; APO-J; SGP-2; SP-40; TRPM2; Apo-J; AAG4; CLU1; CLU2; SGP2 |
| Gene ID |
1191 |
| UniProt ID |
P10909 |
Information
| Introduction |
Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging. CLU is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
