This product is a conjugated anti-Human Clusterin-α Monoclonal antibody (CTJS-724) generated from the Mouse. The antibody can be used for WB, IF, IHC, FC.
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| Clonality | Monoclonal |
| Clone | CTJS-724 |
| Host Animal | Mouse |
| Isotype | IgG1 κ |
| Immunogen | Recombinant human Clusterin-α, a.a. 432-449 |
| Species Reactivity | Human |
| Applications | WB; IF; IHC; FC |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Clusterin-α. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | iFluor® 488 |
| Format | Liquid |
| Size | 200 µg |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | Clusterin-α |
| Alternative Names | Clusterin α chain; Clusterin α subunit |
| Gene ID | 1191 |
| UniProt ID | P10909 |
| Introduction | Clusterin is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. The gene is highly conserved in species, and the protein is widely distributed in many tissues and organs, where it participates in a number of biological processes, including lipid transport, membrane recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis. |