Mouse Anti-Human Clusterin Monoclonal Antibody (CTJS-865)(Cat#: CTA-026)

Name: Mouse Anti-Human Clusterin Monoclonal Antibody (CTJS-865)
SKU: CTA-026
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Clusterin Monoclonal antibody (CTJS-865) generated from the Mouse. The antibody can be used for WB; IF; IHC; IP.

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Datasheet

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Specifications

Clonality	Monoclonal
Clone	CTJS-865
Host Animal	Mouse
Isotype	IgG1
Immunogen	Purified human clusterin (TRPM-2)
Species Reactivity	Human
Applications	WB; IF; IHC; IP
Application Notes	WB: 1:2000 IF: 1:10-1:500 IHC: 1:10-1:500 IHC: -Frozen 1:10-1:500 IHC: -Paraffin 1:10-1:500 IP: 1:10-1:500 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Clusterin.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	25; 100 µg
Storage	4°C
Type	Primary Antibody

Target

Target Name	Clusterin
Alternative Names	Testosterone-Repressed Prostate Message; Clusterin (Complement Lysis Inhibitor, SP-40, 40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J); Apolipoprotein J; Complement-Associated Protein SP-40, 40; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Sulfated Glycoprotein 2; Ku70-Binding Protein 1; NA1/NA2; TRPM-2; APOJ; KUB1; CLI; Aging-Associated Gene 4 Protein; Aging-Associated Protein 4; APO-J; SGP-2; SP-40; TRPM2; Apo-J; AAG4; CLU1; CLU2; SGP2
Gene ID	1191
UniProt ID	P10909

Information

Introduction

Clusterin is a 75 - 80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. It is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, Clusterin is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.