Mouse Anti-Human Complement C3a/C3a desArg Monoclonal Antibody (CTJS-562)(Cat#: CTA-009)

This product is an unconjugated anti-Human Complement C3a/C3a desArg Monoclonal antibody (CTJS-562) generated from the Mouse. The antibody can be used for FC; IHC; Neut.

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Specifications
Clonality Monoclonal
Clone CTJS-562
Host Animal Mouse
Isotype IgG1κ
Immunogen Human complement component C3a
Species Reactivity Human
Applications FC; IHC; Neut
Application Notes IHC: 1:50
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human complement C3a/C3a desArg.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 25 μL
Storage 4°C
Type Primary Antibody
ProAb NeutAb
Target
Target Name C3a
Alternative Names Complement C3a; C3a des-Arg
Gene ID 718
UniProt ID P01024
Information
Introduction Complement C3a is a 77 residue anaphylatoxin formed by the cleavage of complement component 3. C3a can bind to the C3a receptor induce responses. C3a is an effector of the complement system with a range of functions including T cell activation and survival, angiogenesis stimulation, chemotaxis, mast cell degranulation, and macrophage activation. C3a desArg is formed when the C-terminal arginine residue is cleaved off by serum carboxypeptidase B from C3a. C3a desArg binds to the C5L2 receptor inducing a lowered inflammatory function.

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