Mouse Anti-Human Complement C3c Monoclonal Antibody (CTJS-329)(Cat#: CTA-065)
This product is an unconjugated anti-Human Complement C3c Monoclonal antibody (CTJS-329) generated from the Mouse. The antibody can be used for WB; ELISA; FC; IHC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-329 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Human C3 from normal serum, highly purified by chromatography. |
| Species Reactivity |
Human |
| Applications |
WB; ELISA; FC; IHC |
| Application Notes |
WB: 1:100-1:2000
ELISA: 1:100-1:2000
FC: 1:10-1:1000
IHC: 1:10-1:500
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human complement C3c. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
50 µg |
| Storage |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
C3c |
| Alternative Names |
Complement C3c; C3c fragment |
| Gene ID |
718 |
| UniProt ID |
P01024 |
Information
| Introduction |
Complement C3c is a cleaved product of complement C3. During the activation of complement system, C3 is cleaved into C3a and C3b fragments by C3 convertase. The C3b fragment can be degraded into iC3b when cleaved by complement factor I. iC3b serves as 'inactive' C3b unable to associate with complement factor B, which prevents amplification of the complement cascade through the alternative pathway. iC3b will be cleaved by trypsin-like enzymes releasing C3c and C3dg, and C3dg can be further cleaved into C3g and C3d. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
