Mouse Anti-Human Complement C4b/d Monoclonal Antibody (CTJS-795)(Cat#: CTA-105)

This product is an unconjugated anti-Human Complement C4b/d Monoclonal antibody (CTJS-795) generated from the Mouse. The antibody can be used for IF; IHC.

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Summary

Specifications
Clonality Monoclonal
Clone CTJS-795
Host Animal Mouse
Isotype IgG1κ
Immunogen Recombinant human Complement 4d protein
Species Reactivity Human
Applications IF; IHC
Application Notes IF: 1:50-1:100
IHC: 0.5-1.0µg/mL
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human complement C4b/d.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 20; 100 µg
Storage 4°C
Type Primary Antibody
Target
Target Name C4b/d
Alternative Names Complement C4b; Complement C4d
Gene ID 721
UniProt ID P0C0L5
Information
Introduction Complement C4b is a protein fragment released from the cleavege of C4. In the activated complement classical pathway or the lectin pathway, C1s and MASP-2 cleave the complement component 4 (C4) alpha chain into C4a and C4b fragments. C4b is an important member of the complement cascade that participates in the formation of the C3 convertases (C4bC2b) and C5 convertases (C4bC2bC3b).
Complement C4d is a degradation product of C4b when cleaved by Factor I. Complement C4D has been recognized as a marker of complement activation, which has been used as an indicator in the evaluation of cellular and antibody mediated rejection in a variety of tissues.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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