Mouse Anti-Human Complement C4b Monoclonal Antibody (CTJS-523)(Cat#: CTA-103)

This product is an unconjugated anti-Human Complement C4b Monoclonal antibody (CTJS-523) generated from the Mouse. The antibody can be used for WB; ELISA.

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Specifications
Clonality Monoclonal
Clone CTJS-523
Host Animal Mouse
Isotype IgG2b Kappa
Immunogen C4B (1347 a.a. - 1446 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. NNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEG
Species Reactivity Human
Applications WB; ELISA
Application Notes WB: 1:500
ELISA: 1:100-1:2000
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Human complement C4b.
Purity ≥95% as determined by SDS-PAGE
Format Liquid
Size 100 µg
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Type Primary Antibody
Target
Target Name C4b
Alternative Names Complement C4B (Chido Blood Group); C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 3; Complement Component 4B (Chido Blood Group); Basic Complement C4; Complement Component 4B; Chido Form Of C4; Complement C4B1a; Complement C4-B; CH; C4F; CO4; C4B1; C4B2; C4B3; C4B5; C4BD; C4B12; C4B_2; CPAMD3
Gene ID 721
UniProt ID P0C0L5
Information
Introduction Complement C4b is a protein fragment released from the cleavege of C4. In the activated complement classical pathway or the lectin pathway, C1s and MASP-2 cleave the complement component 4 (C4) alpha chain into C4a and C4b fragments. C4b is an important member of the complement cascade that participates in the formation of the C3 convertases (C4bC2b) and C5 convertases (C4bC2bC3b).
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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