Mouse Anti-Human Complement C4BPB Monoclonal Antibody (CTJS-452)(Cat#: CTA-230)

Name: Mouse Anti-Human Complement C4BPB Monoclonal Antibody (CTJS-452)
SKU: CTA-230
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Complement C4BPB Monoclonal antibody (CTJS-452) generated from the Mouse. The antibody can be used for WB; ELISA; IP.

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Datasheet

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Specifications

Clonality	Monoclonal
Clone	CTJS-452
Host Animal	Mouse
Isotype	IgG2a Kappa
Immunogen	C4BPB (1 a.a. - 251 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MFFWCACCLMVAWRVSASDEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVDGEWSSALPVCKLIQEAPKPECEKALLAFQESKNLCEAMENFMQQLKESGMTMEELKYSLELKKAELKAKLL
Species Reactivity	Human
Applications	WB; ELISA; IP
Application Notes	WB: 1:500 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human complement C4BPB.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	100 µg
Storage	Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Type	Primary Antibody

Target

Target Name	C4bPB
Alternative Names	C4b binding protein beta chain; C4b-binding protein beta chain; C4BP; complement component 4 binding protein beta chain; complement component 4 binding protein beta; complement component 4-binding protein beta
Gene ID	725
UniProt ID	P20851

Information

Introduction

C4b-binding protein beta chain is encoded by the human C4BPB gene. It controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.