This product is an unconjugated anti-Human Complement Factor I Monoclonal antibody (CTJS-340) generated from the Mouse. The antibody can be used for FC; IP; IHC; WB.
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| Clonality | Monoclonal |
| Clone | CTJS-340 |
| Host Animal | Mouse |
| Isotype | IgG1κ |
| Immunogen | Factor I isolated from human plasma adsorbed onto aluminum hydroxide gel |
| Species Reactivity | Human |
| Applications | FC; IP; IHC; WB |
| Application Notes | FC: 1:200 IP: 5 µg/mL WB: 1:500 - 1:1000 The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human complement Factor I. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Liquid |
| Size | 100 µg |
| Storage | 4°C |
| Type | Primary Antibody |
| Target Name | Factor I |
| Alternative Names | Konglutinogen-Activating Factor; C3B/C4B Inactivator; C3b-Inactivator; Complement Control Protein Factor I; Complement Factor I Heavy Chain; Light Chain Of Factor I; Complement Component I; I Factor (Complement); EC 3.4.21.45; FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA |
| Gene ID | 3426 |
| UniProt ID | P05156 |
| Introduction | Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein of the complement system, first isolated in 1966 in guinea pig serum, that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b. It is a soluble glycoprotein that circulates in human blood at an average concentration of 35 μg/mL. |