Mouse Anti-Human CR1 Monoclonal Antibody (CTJS-321)(Cat#: CTA-240)

Name: Mouse Anti-Human CR1 Monoclonal Antibody (CTJS-321)
SKU: CTA-240
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human CR1 Monoclonal antibody (CTJS-321) generated from the Mouse. The antibody can be used for FC; ELISA.

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Specifications

Clonality	Monoclonal
Clone	CTJS-321
Host Animal	Mouse
Isotype	IgG1
Immunogen	Mouse myeloma cell line NS0-derived recombinant human CD35 Gln42-Asp1971 (His1208Arg)
Species Reactivity	Human
Applications	FC; ELISA
Application Notes	FC: 2.5 ug/10^6 cells The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human CR1.
Purity	≥95% as determined by SDS-PAGE
Format	Lyophilized
Size	25; 100 µg
Storage	12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Type	Primary Antibody

Target

Target Name	CR1
Alternative Names	Complement C3b/C4b Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; Knops Blood Group Antigen; Complement Receptor 1; C3-Binding Protein; Complement Receptor Type 1; KN; C3BR; C4BR; CD35; Cr1; C3DR; CD21; Cr-1; Cr-2
Gene ID	1378
UniProt ID	P17927

Information

Introduction

Complement receptor 1 (CR1) also known as CD35, cluster of differentiation 35, is a protein that in humans is encoded by the CR1 gene. CR1 can act as a negative regulator of the complement cascade, mediate immune adherence and phagocytosis and inhibit both the classic and alternative pathways. Complement receptor 2 (CR2), also known as CD21, cluster of differentiation 21, is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.