Mouse Anti-Human CR1 Monoclonal Antibody (CTJS-416)(Cat#: CTA-239)
This product is an unconjugated anti-Human CR1 Monoclonal antibody (CTJS-416) generated from the Mouse. The antibody can be used for FC; IHC; IF.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-416 |
| Host Animal |
Mouse |
| Isotype |
IgG1 Kappa |
| Immunogen |
Recombinant human CR1 protein |
| Species Reactivity |
Human; Baboon; Monkey |
| Applications |
FC; IHC; IF |
| Application Notes |
FC: 0.5 - 1 ug/10^6 cells
IHC: 0.5 - 1.0 µg/mL
IF: 1 - 2 µg/mL
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human, Baboon, Monkey CR1. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
20; 100 µg |
| Storage |
4°C |
| Type |
Primary Antibody |
Target
| Target Name |
CR1 |
| Alternative Names |
Complement C3b/C4b Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; Knops Blood Group Antigen; Complement Receptor 1; C3-Binding Protein; Complement Receptor Type 1; KN; C3BR; C4BR; CD35; Cr1; C3DR; CD21; Cr-1; Cr-2 |
| Gene ID |
1378 |
| UniProt ID |
P17927 |
Information
| Introduction |
Complement receptor 1 (CR1) also known as CD35, cluster of differentiation 35, is a protein that in humans is encoded by the CR1 gene. CR1 can act as a negative regulator of the complement cascade, mediate immune adherence and phagocytosis and inhibit both the classic and alternative pathways. Complement receptor 2 (CR2), also known as CD21, cluster of differentiation 21, is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
