This product is an unconjugated anti-Human CR2 Monoclonal antibody (CTJS-320) generated from the Mouse. The antibody can be used for WB; FC.
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| Clonality | Monoclonal |
| Clone | CTJS-320 |
| Host Animal | Mouse |
| Isotype | IgG1 |
| Immunogen | Chinese hamster ovary cell line CHO-derived recombinant human CD21 Ile21-Arg971 |
| Species Reactivity | Human |
| Applications | WB; FC |
| Application Notes | WB: 2 µg/mL FC: 0.25 ug/10^6 cells The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human CR2. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Lyophilized |
| Size | 25; 100 µg |
| Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Type | Primary Antibody |
| Target Name | CR2 |
| Alternative Names | Complement C3d Receptor 2; Complement Component (3d/Epstein Barr Virus) Receptor 2; Complement Component 3d Receptor 2; Epstein-Barr Virus Receptor; EBV Receptor; Complement C3d Receptor; CD21 Antigen; Cr2; CR; C3DR; CD21; CVID7; SLEB9 |
| Gene ID | 1380 |
| UniProt ID | P20023 |
| Introduction | omplement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation. it is receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU, and participates in B lymphocytes activation. |