This product is an unconjugated anti-Human CR2 Monoclonal antibody (CTJS-470) generated from the Mouse. The antibody can be used for IHC; PA.
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| Clonality | Monoclonal |
| Clone | CTJS-470 |
| Host Animal | Mouse |
| Isotype | IgG1 Kappa |
| Immunogen | Recombinant human CR2 (CD21) protein fragment (around aa 44-196) (exact sequence is proprietary) |
| Species Reactivity | Human |
| Applications | IHC; PA |
| Application Notes | IHC: 1-2 µg/mL The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human CR2. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Liquid |
| Size | 20; 100 µg |
| Storage | 4°C |
| Type | Primary Antibody |
| Target Name | CR2 |
| Alternative Names | Complement C3d Receptor 2; Complement Component (3d/Epstein Barr Virus) Receptor 2; Complement Component 3d Receptor 2; Epstein-Barr Virus Receptor; EBV Receptor; Complement C3d Receptor; CD21 Antigen; Cr2; CR; C3DR; CD21; CVID7; SLEB9 |
| Gene ID | 1380 |
| UniProt ID | P20023 |
| Introduction | omplement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation. it is receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU, and participates in B lymphocytes activation. |