Mouse Anti-Human Factor B Ba Monoclonal Antibody (CTJS-144) [Biotin](Cat#: CTA-574)

Name: Mouse Anti-Human Factor B Ba Monoclonal Antibody (CTJS-144) [Biotin]
SKU: CTA-574
Rating: 5 (1 reviews)

This product is a conjugated anti-Human Complement Factor B Ba Monoclonal antibody (CTJS-144) generated from the Mouse. The antibody can be used for ELISA.

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Specifications

Clonality	Monoclonal
Clone	CTJS-144
Host Animal	Mouse
Isotype	IgG1 κ
Immunogen	Factor B purified from human plasma
Species Reactivity	Human
Applications	ELISA
Application Notes	ELISA: 1:200 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Complement Factor B Ba.
Purity	≥95% as determined by SDS-PAGE
Conjugation	Biotin
Format	Liquid
Size	100 µL
Storage	Store in dark at 4°C. Do Not Freeze.
Type	Primary Antibody

Target

Target Name	Factor Ba
Alternative Names	Complement Factor Ba; Complement Factor Ba fragment; Factor Ba fragment; CF Ba
Gene ID	629
UniProt ID	P00751

Information

Introduction

Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.