This product is a conjugated anti-Human Complement Factor B Ba Monoclonal antibody (CTJS-786) generated from the Mouse. The antibody can be used for WB, IF, IHC, FC.
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| Clonality | Monoclonal |
| Clone | CTJS-786 |
| Host Animal | Mouse |
| Isotype | IgG2b κ |
| Immunogen | Human complement factor B |
| Species Reactivity | Human |
| Applications | WB; IF; IHC; FC |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Complement Factor B Ba. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | PE |
| Format | Liquid |
| Size | 200 µg |
| Storage | Store in dark at 4°C. Do Not Freeze. |
| Type | Primary Antibody |
| Target Name | Factor Ba |
| Alternative Names | Complement Factor Ba; Complement Factor Ba fragment; Factor Ba fragment; CF Ba |
| Gene ID | 629 |
| UniProt ID | P00751 |
| Introduction | Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |