Mouse Anti-Human Factor B Bb Monoclonal Antibody (CTJS-668)(Cat#: CTA-590)
This product is an unconjugated anti-Human Complement Factor B Bb Monoclonal antibody (CTJS-668) generated from the Mouse. The antibody can be used for WB, IP, IF, ELISA.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-668 |
| Host Animal |
Mouse |
| Isotype |
IgG1 κ |
| Immunogen |
Recombinant Human complement factor B, a.a. 426-520 |
| Species Reactivity |
Human |
| Applications |
WB; IP; IF; ELISA |
| Application Notes |
WB: 1:100-1:1000
IF: 1:50-1:500
ELISA: 1:30-1:3000
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Complement Factor B Bb. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
200 µg |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
Target
| Target Name |
Factor Bb |
| Alternative Names |
Complement Factor Bb; Complement Factor Bb fragment; Factor Bb fragment; CF Bb |
| Gene ID |
629 |
| UniProt ID |
P00751 |
Information
| Introduction |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
