Mouse Anti-Human Ficolin-1 Monoclonal Antibody (CTJS-176)(Cat#: CTA-1052)

Name: Mouse Anti-Human Ficolin-1 Monoclonal Antibody (CTJS-176)
SKU: CTA-1052
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Ficolin-1 Monoclonal antibody (CTJS-176) generated from the Mouse. The antibody can be used for WB, ELISA.

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Specifications

Clonality	Monoclonal
Clone	CTJS-176
Host Animal	Mouse
Isotype	IgG2a κ
Immunogen	Recombinant human FCN1 with GST tag, a.a. 201-300
Species Reactivity	Human
Applications	WB; ELISA
Application Notes	WB: 1:500 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human Ficolin-1.
Purity	≥95% as determined by SDS-PAGE
Conjugation	Unconjugated
Format	Liquid
Size	100 µg
Storage	Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle.
Type	Primary Antibody

Target

Target Name	Ficolin-1
Alternative Names	Ficolin 1; FCNM ; Ficolin-Alpha; Ficolin-1; M-Ficolin; Ficolin-A; Ficolin (Collagen/Fibrinogen Domain Containing) 1; FCN1
Gene ID	2219
UniProt ID	O00602

Information

Introduction

Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.