Mouse Anti-Human Ficolin-1 Monoclonal Antibody (CTJS-582)(Cat#: CTA-1050)
This product is an unconjugated anti-Human Ficolin-1 Monoclonal antibody (CTJS-582) generated from the Mouse. The antibody can be used for IHC.
Summary
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Specifications
Clonality |
Monoclonal |
Clone |
CTJS-582 |
Host Animal |
Mouse |
Isotype |
IgG1 |
Immunogen |
Recombinant Human FCNA |
Species Reactivity |
Human |
Applications |
IHC |
Application Notes |
IHC: 1:50-1:200 The optimal working dilutions should be determined by the end user. |
Specificity |
This antibody reacts with Human Ficolin-1. |
Purity |
≥95% as determined by SDS-PAGE |
Conjugation |
Unconjugated |
Format |
Liquid |
Size |
100 µL |
Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type |
Primary Antibody |
Target
Target Name |
Ficolin-1 |
Alternative Names |
Ficolin 1; FCNM ; Ficolin-Alpha; Ficolin-1; M-Ficolin; Ficolin-A; Ficolin (Collagen/Fibrinogen Domain Containing) 1; FCN1 |
Gene ID |
2219 |
UniProt ID |
O00602 |
Information
Introduction |
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.