This product is an unconjugated anti-Human Ficolin-3 Monoclonal antibody (CTJS-617) generated from the Mouse. The antibody can be used for ELISA.
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| Clonality | Monoclonal |
| Clone | CTJS-617 |
| Host Animal | Mouse |
| Isotype | IgG1κ |
| Immunogen | Recombinant human H-ficolin |
| Species Reactivity | Human |
| Applications | ELISA |
| Application Notes | ELISA: 1:32000 The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human Ficolin-3. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Liquid |
| Size | 25; 100 µg |
| Storage | 4°C |
| Type | Primary Antibody |
| Target Name | Ficolin-3 |
| Alternative Names | Hakata antigen; Ficolin-3; FCNH; HAKA1; Collagen/Fibrinogen Domain-Containing Lectin 3 P35; Ficolin (Collagen/Fibrinogen Domain Containing) 3 (Hakata Antigen); Ficolin (Collagen/Fibrinogen Domain Containing) 3; H-Ficolin |
| Gene ID | 8547 |
| UniProt ID | O75636 |
| Introduction | Ficolin-3 is a protein that in humans is encoded by the FCN3 gene. Ficolin-3 was initially identified as H-ficolin, in which H is after the Hakata antigen that was previously found as an autoantigen in patients who lived in the city of Hakata. Ficolin-3 has been shown have a calcium-independent lectin activity. It can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. |