Mouse Anti-Human iC3b Monoclonal Antibody (CTJS-775)(Cat#: CTA-1159)
This product is an unconjugated anti-Human Complement iC3b Monoclonal antibody (CTJS-775) generated from the Mouse. The antibody can be used for FC, Neut, ICC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-775 |
| Host Animal |
Mouse |
| Isotype |
IgG1κ |
| Immunogen |
Human Complement C3b/iC3b-Sepharose |
| Species Reactivity |
Human; Primate |
| Applications |
FC; Neut; ICC |
| Application Notes |
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human and Primate Complement C3b/iC3b. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
100 μg |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
| ProAb |
NeutAb |
Target
| Target Name |
iC3b |
| Alternative Names |
inactive C3b; inactivated C3b; iC3b fragment |
| Gene ID |
718 |
| UniProt ID |
01024 |
Information
| Introduction |
Complement iC3b is an inactive form of C3b, which is formed through the cleavage of C3b by factor I in the presence of factor H. Complement receptors on white blood cells are able to bind iC3b, so iC3b functions as an opsonin. Unlike intact C3b, iC3b cannot associate with factor B, thus preventing amplification of the complement cascade through the alternative pathway. Complement factor I can further cleave iC3b into a protein fragment known as C3d. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
