This product is an unconjugated anti-Human MASP-2 Monoclonal antibody (CB-CT048) generated from the Mouse. The antibody can be used for WB, IP, IF, ELISA.
Clonality | Monoclonal |
Clone | CTJS-874 |
Host Animal | Mouse |
Isotype | IgG1 κ |
Immunogen | Recombinant human MASP-2, a.a. 284-343 |
Species Reactivity | Human |
Applications | WB; IP; IF; ELISA |
Application Notes | WB: 1:100-1:1000 IP: 1-2 µg/mL IHC: 1:50-1:500 ELISA: 1:30-1:3000 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human MASP-2. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 200 µg |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | MASP2 |
Alternative Names | Mannan Binding Lectin Serine Peptidase 2; Mannan-Binding Lectin Serine Protease 2; Mannan-Binding Lectin Serine Peptidase 1 Pseudogene 1; Mannose-Binding Protein-Associated Serine Protease 2; MBL-Associated Serine Protease 2; MASP-2; MBL-Associated Plasma Protein Of 19 KD; Small MBL-Associated Protein; MASP1P1; MAP19; MASP2; SMAP |
Gene ID | 10747 |
UniProt ID | O00187 |
Introduction | Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. |