This product is an unconjugated anti-Human MBL2 Monoclonal antibody (CTJS-21) generated from the Mouse. The antibody can be used for WB, ELISA, IHC.
Clonality | Monoclonal |
Clone | CTJS-21 |
Host Animal | Mouse |
Isotype | IgG1 κ |
Epitope | The head-neck region of human MBL. |
Immunogen | MBL derived from human plasma |
Species Reactivity | Human |
Applications | WB; ELISA; IHC |
Application Notes | WB: 1:100-1:2000 ELISA 1:100-1:2000 IHC: 1:10-1:500 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human MBL2. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 25; 100 µL |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | MBL2 |
Alternative Names | Mannose Binding Lectin 2; COLEC1; Mannose-Binding Lectin (Protein C) 2, Soluble (Opsonic Defect); Mannose-Binding Protein C; Collectin-1; MBP-C; MBP1; MBL; Mannose-Binding Lectin 2, Soluble (Opsonic Defect); Mannose-Binding Lectin (Protein C) 2, Soluble; Mannan-Binding Protein; Mannose-Binding Lectin; Mannan-Binding Lectin; HSMBPC; MBL2D; MBPD; MBL2; MBP |
Gene ID | 4153 |
UniProt ID | P11226 |
Introduction | Mannose Binding Lectin (MBL), also called mannan-binding lectin or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity as an opsonin and via the lectin pathway. Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. |