Mouse C5b-9 Terminal Complement Complex ELISA Kit-CTK-357(Cat#: CTK-357)
This product is an ELISA kit for the determination of Mouse C5b-9 Terminal Complement Complex in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Mouse C5b-9 Terminal Complement Complex as low as 0.65 ng/mL.
Summary
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Specifications
Assay Type |
Sandwich ELISA |
Sensitivity |
0.65 ng/mL (1.56-100 ng/mL) |
Pack Size |
96 tests |
Species Reactivity |
Mouse |
Target |
C5b-9 Complex |
Cross Reactivity |
No significant cross-reactions have been observed between Mouse C5b-9 Terminal Complement Complex and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
Applications |
ELISA |
Storage |
4°C |
Information
Introduction |
C5b-9 terminal complement complex, also named as membrane attack complex (MAC), is a complex protein composed of the subunits C5b, C6, C7, C8 and several C9 molecules. The MAC is a structure typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is one of the effector proteins of the immune system. The MAC forms transmembrane channels, which disrupt the cell membrane of target cells, leading to cell lysis and death. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.