Mouse Collectin-11 ELISA Kit(Cat#: CTK-901)

Name: Mouse Collectin-11 ELISA Kit
SKU: CTK-901
Rating: 5 (1 reviews)

This product is an ELISA kit for the in vitro determination of Mouse Collectin-11 in the samples of Serum, Plasma, Tissue Homogenates. It is highly sensitive and available for the detection of Mouse Collectin-11 as low as 0.39 ng/mL.

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Specifications

Assay Type	Sandwich ELISA
Sensitivity	0.39 ng/mL (1.56-100 ng/mL)
Species Reactivity	Mouse
Target	Collectin-11
Cross Reactivity	No significant cross-reactions have been observed between Mouse Collectin-11 and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues.
Applications	ELISA
Storage	Short-term storage at 4°C and long-term storage at -20°C.

Information

Introduction

Collectin-11 (CL-11) is a lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.