This product is an ELISA kit for the determination of Mouse Complement C3 Convertase in the samples of Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate. It is highly sensitive and available for the detection of Mouse Complement C3 Convertase as low as 0.117 ng/mL.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Assay Type | Sandwich ELISA |
| Sensitivity | 0.117 ng/mL (0.312-20 ng/mL) |
| Species Reactivity | Mouse |
| Target | C3 Convertase |
| Cross Reactivity | No significant cross-reactions have been observed between Mouse Complement C3 Convertase and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | 4°C |
| Introduction | Complement C3 convertase is a kind of serine protease that is usually composed of C3bBb in the alternative pathway and C4bC2b in the classical and lectin pathway of the complement system. C3 convertase usually functions by catalyzing the proteolytic cleavage of C3 into C3a and C3b. C3 convertase is a critical part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis. |