This product is a 110 kDa native human C1 Inhibitor protein isolated from normal human serum. It is availible for ELISA, Functional Assays.
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| Specie Reactivity | Human |
| Target | C1 Inhibitor |
| Molecule Mass | 110 kDa |
| Purity | >95% determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 10 mM sodium phosphate, 145 mM NaCl, pH 7.3 |
| Applications | ELISA; Functional Assays |
| Product Form | Frozen liquid |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
| Alternative Names | Serpin Family G Member 1; Plasma Protease C1 Inhibitor; C1IN; Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1; C1 Esterase Inhibitor; C1-Inhibiting Factor;C1-Inhibitor; C1INH; ; Serine/Cysteine Proteinase Inhibitor Clade G Member 1; Epididymis Secretory Sperm Binding Protein; Complement Component 1 Inhibitor; SERPING1; C1-INH; C1Inh |
| Gene ID | 710 |
| UniProt ID | P05155 |