Native Human Complement Component C3C Protein(Cat#: CTP-052)

Name: Native Human Complement Component C3C Protein
SKU: CTP-052
Rating: 5 (1 reviews)

This product is a 137 KDa Native Human Complement Component C3C protein from human plasma.

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Specifications

Specie Reactivity	Human
Target	C3c
Molecule Mass	137 Kda
Purity	>96.0% as determined by SDS-PAGE
Formulation	Sodium phosphate buffer, pH 7.2, containing 0.15M NaCl
Product Form	Lyophilized
Storage	Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles.

Protein Information

Introduction	Complement C3c is a cleaved product of complement C3. During the activation of complement system, C3 is cleaved into C3a and C3b fragments by C3 convertase. The C3b fragment can be degraded into iC3b when cleaved by complement factor I. iC3b serves as 'inactive' C3b unable to associate with complement factor B, which prevents amplification of the complement cascade through the alternative pathway. iC3b will be cleaved by trypsin-like enzymes releasing C3c and C3dg, and C3dg can be further cleaved into C3g and C3d.
Alternative Names	Complement C3c; C3c fragment
Gene ID	718
UniProt ID	P01024

For Research Use Only. Not for Diagnostic or Therapeutic Applications.