This product is an ELISA kit for the determination of Pig Complement C3 Convertase in the samples of Plasma and Serum. It is highly sensitive and available for the detection of Pig Complement C3 Convertase as low as 0.071 ng/mL.
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| Assay Type | Sandwich ELISA |
| Sensitivity | 0.071 ng/mL (0.156-10 ng/mL) |
| Species Reactivity | Porcine |
| Target | C3 Convertase |
| Cross Reactivity | No significant cross-reactions have been observed between Pig Complement C3 Convertase and analogues, but existing techniques may limit the detection of cross-reactions with untested analogues. |
| Applications | ELISA |
| Storage | 4°C |
| Introduction | Complement C3 convertase is a kind of serine protease that is usually composed of C3bBb in the alternative pathway and C4bC2b in the classical and lectin pathway of the complement system. C3 convertase usually functions by catalyzing the proteolytic cleavage of C3 into C3a and C3b. C3 convertase is a critical part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis. |