Rabbit Anti-Human C4a Polyclonal Antiserum(Cat#: CTA-P-008)
This product is an Anti-Human C4a Polyclonal Antiserum from rabbits immunized with highly purified human C4a protein. It is not a purified IgG fraction.
Summary
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Specifications
| Host Animal |
Rabbits |
| Isotype |
IgG |
| Immunogen |
C4a protein |
| Applications |
Western Blots; ELISA; Immunodiffusion |
| Application Notes |
Immunodiffusion: 1/4;
WB: 1/500 to 1/1000;
ELISA: 1/500 to 1/2000 |
| Specificity |
C4a |
| Format |
Frozen liquid |
| Size |
1ml |
| Storage |
Store at 4°C short term. Store at -20°C or below long term. Avoid freeze-thaw cycles. |
Target
| Target Name |
C4a |
| Alternative Names |
Complement C4A (Rodgers Blood Group); C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 2; Complement Component 4A (Rodgers Blood Group); Acidic Complement C4; MHC Class III Region Complement; Complement Component 4A; Rodgers Form Of C4; C4A Anaphylatoxin; Complement C4-A; Acidic C4; C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2 |
| Gene ID |
720 |
| UniProt ID |
P0C0L4 |
Information
| Introduction |
Complement C4-A is a protein that in humans is encoded by the C4A gene.This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
