Rabbit Anti-Human Clusterin Monoclonal Antibody (CTJS-141)(Cat#: CTA-730)
This product is an unconjugated anti-Human Clusterin Monoclonal antibody (CTJS-141) generated from the Rabbit. The antibody can be used for IHC.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-141 |
| Host Animal |
Rabbit |
| Isotype |
IgG |
| Immunogen |
Recombinant Human Clusterin |
| Species Reactivity |
Human |
| Applications |
IHC |
| Application Notes |
IHC: 1:100-1:500
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human Clusterin. |
| Purity |
≥95% as determined by SDS-PAGE |
| Conjugation |
Unconjugated |
| Format |
Liquid |
| Size |
100 µL |
| Storage |
Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type |
Primary Antibody |
Target
| Target Name |
Clusterin |
| Alternative Names |
Clusterin; Testosterone-Repressed Prostate Message; Sulfated Glycoprotein; Apolipoprotein J; TRPM-2; Complement Cytolysis Inhibitor; Complement Lysis Inhibitor; Ku70-Binding Protein 1; SP-40; APOJ; CLU1; CLU2; Aging-Associated Protein 4; APO-J; TRPM2; Apo-J 4; CLU |
| Gene ID |
1191 |
| UniProt ID |
P10909 |
Information
| Introduction |
Clusterin is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. It is a member of the small heat shock protein family and, thus, a molecular chaperone. Unlike most other chaperone proteins, which aid intracellular proteins, CLU is a Golgi chaperone that facilitates the folding of secreted proteins in an ATP-independent way. The gene is highly conserved in species, and the protein is widely distributed in many tissues and organs, where it participates in a number of biological processes, including lipid transport, membrane recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
