Rabbit Anti-Human Complement C4 Monoclonal Antibody (CTJS-63)(Cat#: CTA-099)

Name: Rabbit Anti-Human Complement C4 Monoclonal Antibody (CTJS-63)
SKU: CTA-099
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Complement C4 Monoclonal antibody (CTJS-63) generated from the Rabbit. The antibody can be used for IHC.

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Specifications

Clonality	Monoclonal
Clone	CTJS-63
Host Animal	Rabbit
Isotype	IgG
Immunogen	Peptide derived from internal sequence of human C4.
Species Reactivity	Human
Applications	IHC
Application Notes	IHC: 1:100 - 1:200 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human complement C4.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	100 µL
Storage	4°C
Type	Primary Antibody

Target

Target Name	C4
Alternative Names	Complement C4; Complement Component C4; Complement Component 4 ; C4
Gene ID	720
UniProt ID	P0C0L4

Information

Introduction

Complement C4 is an important member in the complement cascade. Human C4 is a glycosylated protein originating from the human leukocyte antigen system. C4 is homologous to complement C3 and C5, sharing ~30% homology with them. Mature C4 is a trimer protein complex composed of three polypeptide chains: α chain, β chain, and γ chain, which provides a surface for interaction between the antigen-antibody complex and other complement components. Once the complement classical pathway or the lectin pathway were activated, the related activated proteases C1s or MASP-2 immediately cleave complement component 4 (C4) into two fragments C4a and C4b.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.