Rabbit Anti-Human Complement C4A Polyclonal Antibody(Cat#: CTA-307)
This product is an unconjugated anti-Human Complement C4A Polyclonal antibody generated from the Rabbit. The antibody can be used for WB; IHC.
Summary
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Specifications
| Clonality |
Polyclonal |
| Host Animal |
Rabbit |
| Isotype |
IgG |
| Immunogen |
Recombinant protein encompassing a sequence within the N-terminus region of human C4. The exact sequence is proprietary. |
| Species Reactivity |
Human |
| Applications |
WB; IHC |
| Application Notes |
WB: 1:500-1:3000
IHC: 1:100-1:1000
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human complement C4A. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
100 µL |
| Storage |
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
C4a |
| Alternative Names |
Complement C4A (Rodgers Blood Group); C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 2; Complement Component 4A (Rodgers Blood Group); Acidic Complement C4; MHC Class III Region Complement; Complement Component 4A; Rodgers Form Of C4; C4A Anaphylatoxin; Complement C4-A; Acidic C4; C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2 |
| Gene ID |
720 |
| UniProt ID |
P0C0L4 |
Information
| Introduction |
Complement C4-A is a protein that in humans is encoded by the C4A gene.This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
