Rabbit Anti-Human Complement Factor I Polyclonal Antibody(Cat#: CTA-335)

Name: Rabbit Anti-Human Complement Factor I Polyclonal Antibody
SKU: CTA-335
Rating: 5 (1 reviews)

This product is an unconjugated anti-Human Complement Factor I Polyclonal antibody generated from the Rabbit. The antibody can be used for WB; IHC.

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Specifications

Clonality	Polyclonal
Host Animal	Rabbit
Isotype	IgG
Immunogen	This antibody was developed against Recombinant Protein corresponding to amino acids: ETSLAECTFTKRRTMGYQDFADVVCYTQKADSPMDDFFQCVNGKYISQMKACDGINDCGDQSDELCCKACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGCAGFASVAQEETEILTADMDAERRRIKSLLPKLSC
Species Reactivity	Human
Applications	WB; IHC
Application Notes	WB: 0.04 - 0.4 µg/mL IHC: 1:200 - 1:500 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Human complement Factor I.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	100 µL
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Type	Primary Antibody

Target

Target Name	Factor I
Alternative Names	Konglutinogen-Activating Factor; C3B/C4B Inactivator; C3b-Inactivator; Complement Control Protein Factor I; Complement Factor I Heavy Chain; Light Chain Of Factor I; Complement Component I; I Factor (Complement); EC 3.4.21.45; FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA
Gene ID	3426
UniProt ID	P05156

Information

Introduction

Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein of the complement system, first isolated in 1966 in guinea pig serum, that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b. It is a soluble glycoprotein that circulates in human blood at an average concentration of 35 μg/mL.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.