This product is an unconjugated anti-Human MASP-2 Polyclonal antibody generated from the Rabbit. The antibody can be used for ICC, IF, IHC, WB.
Clonality | Polyclonal |
Host Animal | Rabbit |
Isotype | IgG |
Immunogen | Recombinant Human MASP2: PVCEPVCGLS ARTTGGRIYG GQKAKPGDFP WQVLILGGTT AAGALLYDNW VLTAAHAVYE QKHDASALDI RMGTLKRLSP HYTQAWSEAV FIHEGYTHDA GFDNDIALIK LNNKVVINSN ITPICLPRKE AESFMRTDDI GTASGWGL |
Species Reactivity | Human |
Applications | ICC; IF; IHC; WB |
Application Notes | ICC: 0.25-2 µg/mL IF: 0.25-2 µg/mL IHC: 1:20-1:50 WB: 0.04-0.4 µg/mL The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human MASP-2. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 100 µL |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | MASP2 |
Alternative Names | Mannan Binding Lectin Serine Peptidase 2; Mannan-Binding Lectin Serine Protease 2; Mannan-Binding Lectin Serine Peptidase 1 Pseudogene 1; Mannose-Binding Protein-Associated Serine Protease 2; MBL-Associated Serine Protease 2; MASP-2; MBL-Associated Plasma Protein Of 19 KD; Small MBL-Associated Protein; MASP1P1; MAP19; MASP2; SMAP |
Gene ID | 10747 |
UniProt ID | O00187 |
Introduction | Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. |