This product is an unconjugated anti-Human MASP-2 Polyclonal antibody generated from the Rabbit. The antibody can be used for ICC, IF, IHC, WB.
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| Clonality | Polyclonal |
| Host Animal | Rabbit |
| Isotype | IgG |
| Immunogen | Recombinant Human MASP2: PVCEPVCGLS ARTTGGRIYG GQKAKPGDFP WQVLILGGTT AAGALLYDNW VLTAAHAVYE QKHDASALDI RMGTLKRLSP HYTQAWSEAV FIHEGYTHDA GFDNDIALIK LNNKVVINSN ITPICLPRKE AESFMRTDDI GTASGWGL |
| Species Reactivity | Human |
| Applications | ICC; IF; IHC; WB |
| Application Notes | ICC: 0.25-2 µg/mL IF: 0.25-2 µg/mL IHC: 1:20-1:50 WB: 0.04-0.4 µg/mL The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Human MASP-2. |
| Purity | ≥95% as determined by SDS-PAGE |
| Conjugation | Unconjugated |
| Format | Liquid |
| Size | 100 µL |
| Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
| Type | Primary Antibody |
| Target Name | MASP2 |
| Alternative Names | Mannan Binding Lectin Serine Peptidase 2; Mannan-Binding Lectin Serine Protease 2; Mannan-Binding Lectin Serine Peptidase 1 Pseudogene 1; Mannose-Binding Protein-Associated Serine Protease 2; MBL-Associated Serine Protease 2; MASP-2; MBL-Associated Plasma Protein Of 19 KD; Small MBL-Associated Protein; MASP1P1; MAP19; MASP2; SMAP |
| Gene ID | 10747 |
| UniProt ID | O00187 |
| Introduction | Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. |