This product is an unconjugated anti-Human/Mouse/Rat Ficolin-1 Polyclonal antibody generated from the Rabbit. The antibody can be used for WB, IHC.
Clonality | Polyclonal |
Host Animal | Rabbit |
Isotype | IgG |
Immunogen | Recombinant human FCN1, a.a. 30-326 |
Species Reactivity | Human; Mouse; Rat |
Applications | WB; IHC |
Application Notes | WB: 1:500-1:2000 IHC: 1:50-1:200 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Human, Mouse, and Rat Ficolin-1. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 100 µL |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | Ficolin-1 |
Alternative Names | Ficolin 1; FCNM ; Ficolin-Alpha; Ficolin-1; M-Ficolin; Ficolin-A; Ficolin (Collagen/Fibrinogen Domain Containing) 1; FCN1 |
Gene ID | 2219 |
UniProt ID | O00602 |
Introduction | Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. |