Rabbit Anti-Human Vitronectin Polyclonal Antibody(Cat#: CTA-428)
This product is an unconjugated anti-Human Vitronectin Polyclonal antibody generated from the Rabbit. The antibody can be used for WB; ELISA; IHC.
Summary
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Specifications
| Clonality |
Polyclonal |
| Host Animal |
Rabbit |
| Isotype |
IgG |
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human Vitronectin. The exact sequence is proprietary. |
| Species Reactivity |
Human; Mouse |
| Applications |
WB; ELISA; IHC |
| Application Notes |
WB: 1:500-1:3000
IHC: 1:100-1:1000
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human, Mouse Vitronectin. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
100 µL |
| Storage |
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Type |
Primary Antibody |
Target
| Target Name |
Vitronectin |
| Alternative Names |
Serum Spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; VN; Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein); Serum-Spreading Factor; Epibolin; VNT |
| Gene ID |
7448 |
| UniProt ID |
P04004 |
Information
| Introduction |
Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpins (serine protease inhibitors). It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
