Rabbit Anti-Mouse Collectin-11 Monoclonal Antibody (TJL-232) [iFluor® 532](Cat#: CTMM-0322-JL2407)

Name: Rabbit Anti-Mouse Collectin-11 Monoclonal Antibody (TJL-232) [iFluor® 532]
SKU: CTMM-0322-JL2407
Rating: 5 (1 reviews)

This product is an iFluor® 532 conjugated anti-Mouse Complement Collectin-11 Monoclonal antibody (TJL-232) generated from the Rabbit. The antibody can be used for ELISA.

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Specifications

Clonality	Monoclonal
Clone	TJL-232
Host Animal	Rabbit
Isotype	IgG
Immunogen	Recombinant Mouse CL-K1/COLEC11
Species Reactivity	Mouse
Applications	ELISA
Application Notes	ELISA: 1:5000-1:10000 The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Mouse Complement Collectin-11.
Purity	≥95% as determined by SDS-PAGE
Conjugation	iFluor® 532
Format	Liquid
Size	0.1 ml
Storage	Store in dark at 4°C. Do Not Freeze.
Type	Primary Antibody

Target

Target Name	Collectin-11
Alternative Names	Collectin Subfamily Member 11; Collectin Kidney Protein 1; Collectin K1; Collectin-11; CL-K1; Collectin Sub-Family Member 11; CL-K1-Iia; CL-K1-Iib; CL-K1-II; COLEC11; 3MC2; CLK1
Gene ID	71693
UniProt ID	Q3SXB8-1

Information

Introduction

Collectin-11 (CL-11) is a lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migRation of neural crest cells and other cell types during embryogenesis.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.