Rabbit Anti-Mouse CR1/CR2 Monoclonal Antibody (CTJS-1)(Cat#: CTA-041)

Name: Rabbit Anti-Mouse CR1/CR2 Monoclonal Antibody (CTJS-1)
SKU: CTA-041
Rating: 5 (1 reviews)

This product is an unconjugated anti-Mouse CR1/CR2 Monoclonal antibody (CTJS-1) generated from the Rabbit. The antibody can be used for WB; FC; IHC; IP; Funcs.

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Specifications

Clonality	Monoclonal
Clone	CTJS-1
Host Animal	Rabbit
Isotype	IgGκ
Immunogen	Purified mouse CR1
Species Reactivity	Mouse
Applications	WB; FC; IHC; IP; Funcs
Application Notes	The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Mouse CR1/CR2.
Purity	≥95% as determined by SDS-PAGE
Format	Liquid
Size	100 uL
Storage	Stable at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C
Type	Primary Antibody

Target

Target Name	CR1/CR2
Alternative Names	CR1 (CD35): Complement C3b/C4b Receptor 1 (Knops Blood Group); Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Complement Component 3b/4b Receptor 1 (Knops Blood Group); Complement Receptor Type 1; Knops Blood Group Antigen; Complement Receptor 1; C3-Binding Protein; C4BR; KN CR2 (CD21): Complement C3d Receptor 2; Complement Component (3d/Epstein Barr Virus) Receptor 2; Complement Component 3d Receptor 2; Epstein-Barr Virus Receptor 2; EBV Receptor; C3DR; Complement Receptor Type 2; Complement C3d Receptor; CD21 Antigen; CVID7; SLEB9; Cr2; CR
Gene ID	1378 12902 12902 (mouse CD21), 1378 (huamn CD35)
UniProt ID	P17927 P19070; P19070 (Mouse CD21), P17927 (Huamn CD35)

Information

Introduction

Complement receptor 1 (CR1) also known as CD35, cluster of differentiation 35, is a protein that in humans is encoded by the CR1 gene. CR1 can act as a negative regulator of the complement cascade, mediate immune adherence and phagocytosis and inhibit both the classic and alternative pathways. Complement receptor 2 (CR2), also known as CD21, cluster of differentiation 21, is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.