This product is an unconjugated anti-Mouse Complement C5 Monoclonal antibody (CTJS-491) generated from the Rat. The antibody can be used for WB; ELISA; Neut.
Clonality | Monoclonal |
Clone | CTJS-491 |
Host Animal | Rat |
Isotype | IgG2a |
Immunogen | E. coli-derived recombinant mouse Complement Component C5a Asn679-Arg755 |
Species Reactivity | Mouse |
Applications | WB; ELISA; Neut |
Application Notes | WB: 1 µg/mL Neutralization: 0.1-0.5 µg/mL The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Mouse complement C5. |
Purity | ≥95% as determined by SDS-PAGE |
Format | Lyophilized |
Size | 25; 100; 500 µg |
Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Type | Primary Antibody |
ProAb | NeutAb |
Target Name | C5 |
Alternative Names | C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement Component 5; C5a Anaphylatoxin; Prepro-C5; CPAMD4; ECLZB |
Gene ID | 727 |
UniProt ID | P01031 |
Introduction | In humans, Complement component 5 is a protein encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved into C5a and C5b: C5a plays an important role in chemotaxis.C5b forms the first part of the complement membrane attack complex. Deficiency is thought to cause Leiner's disease. Complement component 5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is composed of alpha and beta polypeptide chains that are linked by a disulfide bridge. |