Rat Anti-Mouse Complement C5 Monoclonal Antibody (CTJS-491)(Cat#: CTA-116)

Name: Rat Anti-Mouse Complement C5 Monoclonal Antibody (CTJS-491)
SKU: CTA-116
Rating: 5 (1 reviews)

This product is an unconjugated anti-Mouse Complement C5 Monoclonal antibody (CTJS-491) generated from the Rat. The antibody can be used for WB; ELISA; Neut.

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Specifications

Clonality	Monoclonal
Clone	CTJS-491
Host Animal	Rat
Isotype	IgG2a
Immunogen	E. coli-derived recombinant mouse Complement Component C5a Asn679-Arg755
Species Reactivity	Mouse
Applications	WB; ELISA; Neut
Application Notes	WB: 1 µg/mL Neutralization: 0.1-0.5 µg/mL The optimal working dilutions should be determined by the end user.
Specificity	This antibody reacts with Mouse complement C5.
Purity	≥95% as determined by SDS-PAGE
Format	Lyophilized
Size	25; 100; 500 µg
Storage	12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Type	Primary Antibody
ProAb	NeutAb

Target

Target Name	C5
Alternative Names	C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement Component 5; C5a Anaphylatoxin; Prepro-C5; CPAMD4; ECLZB
Gene ID	727
UniProt ID	P01031

Information

Introduction

In humans, Complement component 5 is a protein encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved into C5a and C5b: C5a plays an important role in chemotaxis.C5b forms the first part of the complement membrane attack complex. Deficiency is thought to cause Leiner's disease. Complement component 5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is composed of alpha and beta polypeptide chains that are linked by a disulfide bridge.

For Research Use Only. Not for Diagnostic or Therapeutic Applications.