This product is an unconjugated anti-Mouse MBL1 Monoclonal antibody (CTJS-39) generated from the Rat. The antibody can be used for WB, IA, IF, IHC.
Clonality | Monoclonal |
Clone | CTJS-39 |
Host Animal | Rat |
Isotype | IgG2a |
Immunogen | Mouse MBL-A |
Species Reactivity | Mouse |
Applications | WB; IA; IF; IHC |
Application Notes | WB: 1:100-1:2000 IF: 1:10-1:500 IHC: 1:10-1:500 The optimal working dilutions should be determined by the end user. |
Specificity | This antibody reacts with Mouse MBL1. |
Purity | ≥95% as determined by SDS-PAGE |
Conjugation | Unconjugated |
Format | Liquid |
Size | 50 µg |
Storage | Store at 4°C for short term. Store at -20°C for long term. Avoid freeze-thaw cycle. |
Type | Primary Antibody |
Target Name | MBL1 |
Alternative Names | MBL; MBP; MBL-A; MBP-A; S-MBPMannan-binding protein; Ra-reactive factor polysaccharide-binding component p28B; RaRF p28B |
Gene ID | 17194 |
UniProt ID | P39039 |
Introduction | MBL1, also known as Mannose-binding protein A, is a member of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. It plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. |