Rat Anti-Mouse Vitronectin Monoclonal Antibody (CTJS-764)(Cat#: CTA-185)

This product is an unconjugated anti-Mouse Vitronectin Monoclonal antibody (CTJS-764) generated from the Rat. The antibody can be used for IHC.

Summary Related Products & Services

Specifications
Clonality Monoclonal
Clone CTJS-764
Host Animal Rat
Isotype IgG2a
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Vitronectin
Asp20-Lys478
Species Reactivity Mouse
Applications IHC
Application Notes IHC: 8-25 µg/mL
The optimal working dilutions should be determined by the end user.
Specificity This antibody reacts with Mouse Vitronectin.
Purity ≥95% as determined by SDS-PAGE
Format Lyophilized
Size 25; 100 µg
Storage 12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Type Primary Antibody
Target
Target Name Vitronectin
Alternative Names Serum Spreading Factor; Complement S-Protein; Somatomedin B; S-Protein; V75; VN; Vitronectin (Serum Spreading Factor, Somatomedin B, Complement S-Protein); Serum-Spreading Factor; Epibolin; VNT
Gene ID 7448
UniProt ID P04004
Information
Introduction Vitronectin (VTN or VN) is a glycoprotein of the hemopexin family which is abundantly found in serum, the extracellular matrix and bone.In humans it is encoded by the VTN gene. Vitronectin binds to integrin alpha-V beta-3 and thus promotes cell adhesion and spreading. It also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpins (serine protease inhibitors). It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy.
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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