This product is a 22.6 kDa recombinant human C8G protein with a N-Terminal His-tag expressed in the E. coli.
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| Expressed Host | E. Coli |
| Specie Reactivity | Human |
| Target | C8G |
| Molecule Mass | 22.6 kDa |
| Purity | >95% pure by SDS-PAGE |
| Formulation | 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2 mM DTT, 0.15M NaCl |
| Product Form | Liquid |
| Storage | Store at -20/-80°C. Aliquot to avoid repeated freezing and thawing. |
| Introduction | C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. |
| Alternative Names | C8C; complement component 8, gamma polypeptide; complement component C8 gamma chain; MGC142186 |
| Gene ID | 733 |
| UniProt ID | P07360 |