Recombinant Human CD55 Protein-6His tag(Cat#: CTP-216)
This product is a 36.0 kDa recombinant human CD55 protein with a 6-His tag at the C-terminus expressed in the mouse myeloma cell line, NS0. It is available for Binding Activity Assays.
Summary
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Specifications
| Expressed Host |
Mouse myeloma cell line, NS0 |
| Specie Reactivity |
Human |
| Target |
CD55 |
| Molecule Mass |
36.0 kDa |
| Purity |
>95% by SDS-PAGE under reducing conditions and visualized by silver stain |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
PBS with BSA |
| Applications |
Binding Activity Assays |
| Product Form |
Lyophilized |
| Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
| Introduction |
Complement decay-accelerating factor recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. It acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5, and a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21 during microbial infection. |
| Alternative Names |
CD55 Molecule (Cromer Blood Group); CD55 Molecule, Decay Accelerating Factor For Complement (Cromer Blood Group); Complement Decay-Accelerating Factor; CD55 Antigen; DAF; CR; Decay Accelerating Factor For Complement (CD55, Cromer Blood Group System); Cromer Blood Group Antigen; CHAPLE; CROM; TC |
| Gene ID |
1604 |
| UniProt ID |
P08174 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
