Recombinant Human CD59 Protein-10His tag(Cat#: CTP-219)

Name: Recombinant Human CD59 Protein-10His tag
SKU: CTP-219
Rating: 5 (1 reviews)

This product is a 10.3 kDa recombinant human CD59 protein with a C-terminal 10-His tag expressed in the mouse myeloma cell line, NS0. It is available for Bioactivity Assays.

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Specifications

Expressed Host	Mouse myeloma cell line, NS0
Specie Reactivity	Human
Target	CD59
Molecule Mass	10.3 kDa
Purity	>95% by SDS-PAGE under reducing conditions and visualized by silver stain
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	PBS
Applications	Bioactivity Assays
Product Form	Lyophilized
Storage	Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles.

Protein Information

Introduction	CD59 glycoprotein is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
Alternative Names	CD59 Molecule (CD59 Blood Group); CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5, EJ16, EJ30, EL32 And G344); CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; Membrane Inhibitor Of Reactive Lysis; 20 KDa Homologous Restriction Factor; CD59 Glycoprotein; MEM43 Antigen; 1F5 Antigen; Protectin; HRF-20; MAC-IP; MIC11; MSK21; HRF20; Surface Anitgen Recognized By Monoclonal Antibody 16.3A5; Membrane Attack Complex (MAC) Inhibition Factor; CD59 Antigen, Complement Regulatory Protein; Lymphocytic Antigen CD59/MEM43; Human Leukocyte Antigen MIC11; T Cell-Activating Protein; CD59 Blood Group Antigen; MAC-Inhibitory Protein; Ly-6-Like Protein; CD59 Molecule; CD59 Antigen; 16.3A5; P18-20
Gene ID	966
UniProt ID	P13987

For Research Use Only. Not for Diagnostic or Therapeutic Applications.