Recombinant Human Collectin-11 Protein-N-terminal 6XHis tag(Cat#: CTP-444)

Name: Recombinant Human Collectin-11 Protein-N-terminal 6XHis tag
SKU: CTP-444
Rating: 5 (1 reviews)

This product is a recombinant human Collectin-11 protein with a N-terminal 6XHis tag tag expressed in the Yeast. It is availible for WB, ELISA.

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Specifications

Expressed Host	Yeast
Specie Reactivity	Human
Target	Collectin-11
Purity	>85 % determined by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	Tris-base, 50% glycerol
Applications	WB; ELISA
Product Form	Liquid
Storage	Store at -20°C/-80°C. Avoid freeze-thaw cycles.

Protein Information

Introduction	Collectin-11 (CL-11) is a lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis.
Alternative Names	Collectin Subfamily Member 11; Collectin Kidney Protein 1; Collectin K1; Collectin-11; CL-K1; Collectin Sub-Family Member 11; CL-K1-Iia; CL-K1-Iib; CL-K1-II; COLEC11; 3MC2; CLK1
Gene ID	78989
UniProt ID	Q9BWP8

For Research Use Only. Not for Diagnostic or Therapeutic Applications.