This product is a 49.4 kDa recombinant human Complement 1 Inhibitor expressed in the CHO cells. It is available for Activity Assays.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Expressed Host | CHO Cells |
| Specie Reactivity | Human |
| Target | C1 Inhibitor |
| Molecule Mass | 49.4 kDa |
| Purity | ≥95% by SDS-PAGE and HPLC analyses |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | 10mM Sodium Phosphate, pH 7.5 |
| Applications | Activity Assays |
| Product Form | Lyophilized |
| Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
| Introduction | Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
| Alternative Names | Plasma protease C1 inhibitor; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1; C1IN; C1NH; HAE1; HAE2; C1INH |
| Gene ID | 710 |
| UniProt ID | P05155 |