Recombinant Human Complement 1 Inhibitor(Cat#: CTP-033)
This product is a 49.4 kDa recombinant human Complement 1 Inhibitor expressed in the CHO cells. It is available for Activity Assays.
Summary
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Specifications
| Expressed Host |
CHO Cells |
| Specie Reactivity |
Human |
| Target |
C1 Inhibitor |
| Molecule Mass |
49.4 kDa |
| Purity |
≥95% by SDS-PAGE and HPLC analyses |
| Endotoxin |
<1.0EU per 1µg (determined by the LAL method) |
| Formulation |
10mM Sodium Phosphate, pH 7.5 |
| Applications |
Activity Assays |
| Product Form |
Lyophilized |
| Storage |
Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
Protein Information
| Introduction |
Activation of the C1 complex is under control of the C1-inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. |
| Alternative Names |
Plasma protease C1 inhibitor; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1; C1IN; C1NH; HAE1; HAE2; C1INH |
| Gene ID |
710 |
| UniProt ID |
P05155 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
