This product is a recombinant human C1S protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for WB, ELISA, IP.
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| Expressed Host | E.coli |
| Specie Reactivity | Human |
| Target | C1S |
| Purity | >95 % determined by SDS-PAGE |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
| Applications | WB; ELISA; IP |
| Product Form | Lyophilized |
| Storage | Store at -20°C/-80°C. Avoid freeze-thaw cycles. |
| Introduction | C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. It cleaves the Arg-|-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase. |
| Alternative Names | Complement C1s; Complement Component 1, S Subcomponent; Complement Component 1 Subcomponent S; Complement C1s Subcomponent; C1 Esterase; Basic Proline-Rich Peptide IB-1; C1S |
| Gene ID | 716 |
| UniProt ID | P09871 |