Recombinant Human Complement C5 Protein-N-terminal His Tag(Cat#: CTP-263)

Name: Recombinant Human Complement C5 Protein-N-terminal His Tag
SKU: CTP-263
Rating: 5 (1 reviews)

This product is a 42kDa recombinant human C5 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB.

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Specifications

Expressed Host	E.coli
Specie Reactivity	Human
Target	C5
Molecule Mass	42kDa
Purity	>90 % determined by SDS-PAGE
Endotoxin	<1.0EU per 1µg (determined by the LAL method)
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Applications	Positive Control; Immunogen; WB
Product Form	Lyophilized
Storage	Store at -20°C/-80°C. Avoid freeze-thaw cycles.

Protein Information

Introduction	Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Alternative Names	Complement C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; Complement Component 5; C5a Anaphylatoxin; Prepro-C5; C5a; C5b; Anaphylatoxin C5a Analog; C5
Gene ID	727
UniProt ID	P01031

For Research Use Only. Not for Diagnostic or Therapeutic Applications.