This product is a 8.3 kDa recombinant human Complement Component C5a protein expressed in the E. coli. It is available for Bioactivity Assays.
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| Expressed Host | E. Coli |
| Specie Reactivity | Human |
| Target | C5a |
| Molecule Mass | 8.3 kDa |
| Purity | >95% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining |
| Endotoxin | <1.0EU per 1µg (determined by the LAL method) |
| Formulation | PBS with BSA |
| Applications | Bioactivity Assays |
| Product Form | Lyophilized |
| Storage | Store at 2 to 8°C after reconstitution for short term (1-2 weeks). For long term storage, aliquot and store at -20 or -80°C. Avoid repeated freezing and thawing cycles. |
| Introduction | Complement C5a, together with C5b, are protein fragments released from cleavage of complement component C5 by protease C5-convertase. C5a is a chemotactic agent, as well as an anaphylatoxin, playing critical roles in migration and adherence of neutrophils and monocytes, smooth muscle contraction, and vascular permeability increase. |
| Alternative Names | Complement C5a; C5a fragment; C5a anaphylatoxin |
| Gene ID | 727 |
| UniProt ID | P01031 |